Double vision is the experience of seeing duplicated vision, similar to when one crosses their eyes. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as alcohol, quetiapine, ketamine, and DXM.

An internal hallucination is the perception of a visual hallucination that exclusively occurs within an imagined environment that can typically only be viewed with closed eyes, similar to those found within dreams. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.

Acuity suppression is the degradation of the sharpness and clarity of one's vision, resulting in vision becoming partially to completely blurred and indistinct. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as alcohol, quetiapine, ketamine, and DXM.

Visual disconnection is the experience of becoming distanced and/or detached from one's sense of vision. It is a near-universal effect under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.

Physical euphoria can be described as feelings of pleasure and comfort within and across one's body. This euphoria typically feels somewhat comparable to the endorphin rushes felt during states of excitement or love, the coziness of a comfortable bed, and the rush of an orgasm. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as opioids, stimulants, psychedelics, and GABAergics.

Respiratory depression can be described as a reduced urge to breathe that can be fatal depending on its intensity. It is most commonly induced under the influence of heavy dosages of depressant compounds, particularly opioids, such as heroin and fentanyl, or GABAergics, such as alcohol and GHB. However, it is worth noting that otherwise safe dosages of these compounds can become fatal when combined with even small amounts of other classes of depressant.

Changes in felt gravity can be described as feeling that the pull of gravity has shifted in its direction. For example, during this state one may feel as if they are floating forwards, backwards, upwards, downwards, or in an unspecifiable direction.

Constipation can be described as bowel movements that are infrequent or hard to pass. It usually results in painful defecation and small, compact faeces. It is most commonly induced under the influence of heavy dosages of opioid compounds, such as heroin, tramadol, fentanyl, and kratom.

Dizziness can be described as the perception of a spinning or swaying motion which typically causes a difficulty in standing or walking. It is most commonly induced under the influence of heavy dosages of GABAergic depressant compounds, such as benzodiazepines, alcohol, and GHB.

Increased libido can be described as a distinct increase in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of stimulant compounds, particularly dopaminergic stimulants such as methamphetamine and cocaine.

Motor control loss can be described as feeling as if there has been a distinct decrease in a person's ability to control their physical body with precision, balance, coordination, and dexterity. Motor control loss is often accompanied by other coinciding effects such as sedation and disinhibition. It is most commonly induced under the influence of moderate dosages of GABAergic depressant compounds, such as, alcohol, benzodiazepines, GHB, and phenibut.

Muscle relaxation can be described as the experience of muscles losing their rigidity or tenseness while becoming relaxed and comfortable. It is most commonly induced under the influence of moderate dosages of depressant compounds, such as various benzodiazepines, GABAergics, and opioids.

Sedation can be described as a decrease in a person's physical energy levels which are interpreted as discouraging when it comes to wakefulness, movement, performing tasks, talkativeness, and general exercise. It is most commonly induced under the influence of moderate dosages of depressant compounds, such as opioids, GABAergics, and antipsychotics.

Analysis suppression is a distinct decrease in a person's overall ability to process information and logically or creatively analyze concepts, ideas, and scenarios. It is most commonly induced under the influence of heavy dosages of antipsychotic compounds, and is associated with long term use of such drugs like quetiapine, haloperidol, and risperidone.

Anxiety suppression (also known as anxiolysis or minimal sedation) is medically recognized as a partial to complete suppression of a person’s ability to feel anxiety, general unease, and negative feelings of both psychological and physiological tension. It is most commonly induced under the influence of moderate dosages of anxiolytic compounds which primarily include GABAergic depressants, such as benzodiazepines, alcohol, GHB, and gabapentinoids.

Autonomous voice communication is the experience of being able to hear and converse with a disembodied and audible voice of unknown origin which seemingly resides within one's own head. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds such as psychedelics, dissociatives, and deliriants.

Cognitive euphoria (semantically the opposite of cognitive dysphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of well-being, elation, happiness, excitement, and joy. It is most commonly induced under the influence of moderate dosages of opioids, entactogens, stimulants, and GABAergic depressants. However, it can also occur to a lesser extent under the influence of hallucinogenic compounds such as psychedelics, dissociatives, and cannabinoids.

Compulsive redosing is the experience of a powerful and difficult to resist urge to continuously redose a psychoactive substance in an effort to increase or maintain the subjective effects which it induces. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as opioids, stimulants, GABAergics, and entactogens.

Disinhibition is medically recognized as an orientation towards immediate gratification, leading to impulsive behavior driven by current thoughts, feelings, and external stimuli, without regard for past learning or consideration of future consequences. It is most commonly induced under the influence of moderate dosages of GABAergic depressants, such as alcohol, benzodiazepines, phenibut, and GHB.

Dream potentiation is an effect that increases the subjective intensity, vividness, and frequency of sleeping dream states. It is most commonly induced under the influence of moderate dosages of oneirogenic compounds, a class of hallucinogen that is used to specifically potentiate dreams when taken before sleep.

Increased music appreciation is a general sense of an increased enjoyment of music. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids

Thought deceleration is the process of thought being slowed down significantly in comparison to that of normal sobriety. It is most commonly induced under the influence of heavy dosages of depressant compounds, such as GABAergics, antipsychotics, and opioids.