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Mescaline
Also known as peyote, san pedro, cactus, buttons
Mescaline
Peyote · San Pedro · Cactus · Buttons
Overview
A psychedelic of the phenethylamine family. The drug is found in many cacti, such as Peyote and San Pedro, and has a long history of use. Mescaline can be found naturally and is often syntheized as a synthetic compound.
Sources & licencesPsychonautWiki·TripSit·PubChem chemical identifiers
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COC1=CC(=CC(=C1OC)OC)CCNTags2 tags
Dose
?
Doses are for Mescaline HCl
Safety
- Addiction potential
- not habit-forming
- Full tolerance
- almost immediately after ingestion
- Half tolerance
- 3 days
- Zero tolerance
- 7 days
- Cross-tolerance with
- psychedelic
EffectsPsychonautWikiEffectIndex
Visual
19After images
After images (also known as palinopsia) are visual perceptions that continue to appear in one's vision after exposure to the original image has ceased. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Autonomous entity
An autonomous entity is the experience of perceived contact with beings that appear to be sentient in their behaviour. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds.
Open full explainer on EffectIndex↗Colour enhancement
Colour enhancement is a perceived intensification of the brightness and vividness of colours in the external environment. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Colour shifting
Colour shifting is when objects within the environment fluidly change their colour through a continuously repeating cycle. It is most commonly induced under the influence of psychedelic compounds.
Open full explainer on EffectIndex↗Drifting
Drifting is the experience of the texture, shape, and general structure of objects and scenery appearing progressively warped, melted, and morphed across themselves. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗External hallucination
An external hallucination is the perception of a visual hallucination that displays itself seamlessly into the external environment as if it were physically present. They are most commonly induced under the influence of heavy dosages of deliriant compounds.
Open full explainer on EffectIndex↗Geometry
Geometry is the experience of a person's field of vision becoming partially or completely encompassed by fast-moving, colourful, and extremely complex geometric patterns, form constants, shapes, fractals, and colours.
Open full explainer on EffectIndex↗Increased pareidolia
Increased pareidolia is an increase in a person's ability and tendency to recognise patterns (usually faces) within vague stimuli. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Internal hallucination
An internal hallucination is the perception of a visual hallucination that exclusively occurs within an imagined environment that can typically only be viewed with closed eyes, similar to those found within dreams. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Perspective hallucination
A perspective hallucination is an alteration of the perspective through which a given internal or external hallucination is seen through. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Pupil dilation
Pupil dilation can be described as the enlargement of the size of a person's pupils under normal lighting conditions. This is most commonly induced under the influence of moderate dosages of a wide variety of serotonergic compounds, such as psychedelics, dissociatives, deliriants, entactogens, various stimulants, and some antidepressants.
Open full explainer on EffectIndex↗Recursion
Recursion is a visual distortion that alters the appearance of one's external environment by repeating specific sections of itself across itself in a self-similar fashion. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Scenery slicing
Scenery slicing is the experience of a person's visual field appearing to split into separate, cleanly cut sections. These individual slices then proceed to drift slowly away from their original position before disappearing and resetting to normal. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Settings, sceneries, and landscapes
Settings, sceneries, and landscapes are the perceived environments in which the plot of an internal or external hallucination occurs. This effect is capable of manifesting in a seemingly infinite variety of potential places and settings. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Symmetrical texture repetition
Symmetrical texture repetition is the perception of textures becoming mirrored repeatedly over their own surface in an intricate and symmetrical fashion that is consistent across itself. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Tracers
Tracers are the experience of visual trails of varying lengths and opacity being left behind moving objects. They are most commonly induced under the influence of mild dosages of psychedelic compounds.
Open full explainer on EffectIndex↗Transformations
Transformations are the experience of a perceived visual metamorphosis that specific parts of one's external environment undergo as they shapeshift into other objects. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Visual acuity enhancement
Visual acuity enhancement is a heightening of the clearness and clarity of vision. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Visual exposure to semantic concept network
Visual exposure to semantic concept network is the experience of percieving a seemingly infinite mass of complex interconnected geometric forms comprised entirely of innately understandable representations. These individual geometric representations are perceived to simultaneously convey every internally stored concept and memory contained within the mind.
Open full explainer on EffectIndex↗Emotional & social
1Physical euphoria
Physical euphoria can be described as feelings of pleasure and comfort within and across one's body. This euphoria typically feels somewhat comparable to the endorphin rushes felt during states of excitement or love, the coziness of a comfortable bed, and the rush of an orgasm. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as opioids, stimulants, psychedelics, and GABAergics.
Open full explainer on EffectIndex↗Physical & bodily
10Appetite suppression
Appetite suppression can be described as the experience of a distinct decrease in a person's sense of hunger and appetite in a manner which can result in both a lesser desire to eat food and a decreased enjoyment of its taste. It is most commonly induced under the influence of moderate dosages of stimulant compounds, such as amphetamine, methylphenidate, nicotine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Bodily control enhancement
Bodily control enhancement can be described as feeling as if there has been a distinct increase in a person's ability to control their physical body with precision, balance, coordination, and dexterity. It is most commonly induced under the influence of moderate dosages of stimulating psychedelics, such as LSD, 2C-B, and DOC.
Open full explainer on EffectIndex↗Frequent urination
Frequent urination, or urinary frequency, can be defined as the need to urinate more often than usual. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as stimulants, psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Increased heart rate
Increased heart rate or tachycardia is described as a heart rate that is faster than the normal heart rate at rest. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.
Open full explainer on EffectIndex↗Increased libido
Increased libido can be described as a distinct increase in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of stimulant compounds, particularly dopaminergic stimulants such as methamphetamine and cocaine.
Open full explainer on EffectIndex↗Increased salivation
Increased salivation can be described as the production and excretion of excess saliva within the mouth, which may also be caused by decreased clearance of saliva. It is most commonly induced under the influence of heavy dosages of psychedelic tryptamine compounds, such as psilocybin, 4-AcO-DMT, and 4-HO-MET.
Open full explainer on EffectIndex↗Nausea
Nausea can be described as a sensation of unease and discomfort in the upper stomach combined with an involuntary urge to vomit. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, deliriants, dissociatives, and stimulants.
Open full explainer on EffectIndex↗Seizure
An epileptic seizure (colloquially a fit) can be described as a brief episode of signs and/or symptoms which are due to abnormal, excessive, or synchronous neuronal activity in the brain. They are most commonly induced under the influence of withdrawals from prolonged chronic benzodiazepine or alcohol usage.
Open full explainer on EffectIndex↗Stamina enhancement
Stamina enhancement can be described as an increased ability to engage in physically and mentally taxing activities without the development of fatigue. It most commonly occurs under the influence of stimulants such as amphetamine and specific psychedelics such as LSD.
Open full explainer on EffectIndex↗Stimulation
Stimulation can be described as an increase in a person's physical energy levels. It is most commonly induced under the influence of stimulant compounds, such as amphetamine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Transpersonal & hallucinatory
1Scenarios and plots
Scenarios and plots are the situations, stories, and events that occur within both external and internal hallucinations. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Other
1Synaesthesia
Synaesthesia (also spelt synesthesia or synæsthesia) is the experience of a blending, merging, or mixing of the senses. Synaesthesia is commonly induced under the influence of heavy dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Auditory
3Auditory distortion
An auditory distortion is the experience of perceived alterations in how audible noises present and structure themselves. They are most commonly induced under the influence of hallucinogenic compounds.
Open full explainer on EffectIndex↗Auditory enhancement
An auditory enhancement is the experience of an increase or improvement of the acuteness and clarity of sound. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Auditory hallucination
An auditory hallucination is the experience of hearing spontaneous and imaginary noises. They are most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.
Open full explainer on EffectIndex↗Tactile
3Muscle twitching
Muscle twitching can be described as the sensation of small and localised tremblings of muscle groups. These vibrations are often powerful enough to be visibly seen through the skin. It is most commonly induced under the influence of moderate dosages of stimulating psychedelic compounds such as LSD, 2C-E, DOC, and AMT.
Open full explainer on EffectIndex↗Spontaneous tactile sensations
Spontaneous tactile sensations are the experience of sensations across the body occurring without any obvious or immediate physical trigger. This results in feelings of seemingly random yet distinct tingling sensations that occur across the skin and within the body. Depending on the psychoactive substance consumed, these vary greatly in their styles of sensation.
Open full explainer on EffectIndex↗Tactile enhancement
Tactile enhancement is an overall increase in both the intensity of a person's sense of touch and their awareness of the physical sensations across their body. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Smell & taste
1Olfactory enhancement
Olfactory enhancement (also known as hyperosmia) is the experience of smells becoming significantly richer, stronger, and more noticeable than they would be during everyday sobriety. This experience can either be positive or negative depending on the smell and the person's prior opinion of them. For example, while certain smells such as food or flowers may become a true delight during this experience, other smells such as pollution or body odour may become overpoweringly uncomfortable, which can potentially trigger nausea and vomiting.
Open full explainer on EffectIndex↗Cognitive
26Analysis enhancement
Analysis enhancement is a perceived improvement of a person's overall ability to logically process information or creatively analyze concepts, ideas, and scenarios. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, nicotine, and caffeine.
Open full explainer on EffectIndex↗Autonomous voice communication
Autonomous voice communication is the experience of being able to hear and converse with a disembodied and audible voice of unknown origin which seemingly resides within one's own head. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Cognitive euphoria
Cognitive euphoria (semantically the opposite of cognitive dysphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of well-being, elation, happiness, excitement, and joy. It is most commonly induced under the influence of moderate dosages of opioids, entactogens, stimulants, and GABAergic depressants. However, it can also occur to a lesser extent under the influence of hallucinogenic compounds such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Conceptual thinking
Conceptual thinking is an alteration to the nature and content of one's internal thought stream. This alteration predisposes a user to think thoughts that are no longer primarily comprised of words and linear sentence structures. Instead, thoughts become equally comprised of what is perceived to be extremely detailed renditions of the innately understandable and internally stored concepts that words exist to label. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics and dissociatives.
Open full explainer on EffectIndex↗Creativity enhancement
Creativity enhancement is a perceived increase in one's capability to imagine new ideas, create art, or think about existing concepts in a novel manner. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Delusion
A delusion is a false idea or belief that is held with strong conviction and subjective certainty and is inconsistent with an individual’s educational, cultural and social background. Delusions are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.
Open full explainer on EffectIndex↗Depression reduction
Depression reduction is the experience of minimizing the symptoms associated with depression and low mood states. It most commonly occurs at varying levels of efficacy under the influence of a range of different substances, primarily psychedelics in combination with psychotherapy, or dissociatives.
Open full explainer on EffectIndex↗Emotion intensification
Emotion intensification is an increase in a person's current emotional state beyond normal levels of intensity. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Empathy, affection, and sociability enhancement
Empathy, affection, and sociability enhancement is the experience of a mind state that is dominated by intense feelings of compassion, talkativeness, and happiness. It is most commonly induced under the influence of moderate dosages of entactogenic compounds, such as MDMA, 4-FA, and 2C-B.
Open full explainer on EffectIndex↗Existential self-realization
Existential self-realization can be described as a sudden realization, revelation, or reaffirmation of a person's existence within this universe. Existential self-realization is most commonly induced under the influence of moderate dosages of psychedelic and dissociative compounds such as ketamine, LSD, 4-AcO-DMT, and DCK.
Open full explainer on EffectIndex↗Focus enhancement
Focus enhancement is the experience of an increased ability to selectively concentrate on an aspect of the environment while ignoring other things. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, modafinil, and caffeine
Open full explainer on EffectIndex↗Immersion enhancement
Immersion enhancement is an effect that results in a pronounced increase in one's tendency to become fully captivated and engrossed by external stimuli, such as film, TV shows, video games, and various other forms of media. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Increased music appreciation
Increased music appreciation is a general sense of an increased enjoyment of music. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids
Open full explainer on EffectIndex↗Increased suggestibility
Increased suggestibility is a greater tendency to accept and act on the suggestions of others. It most commonly occurs under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, deliriants, and cannabinoids.
Open full explainer on EffectIndex↗Memory suppression
Memory suppression is an inhibition of a person's ability to maintain a functional short and long-term memory. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Motivation enhancement
Motivation enhancement is an increased desire to perform tasks and accomplish goals in a productive manner. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, nicotine, and modafinil.
Open full explainer on EffectIndex↗Novelty enhancement
Novelty enhancement is a feeling of increased fascination, awe, and appreciation attributed to specific parts or the entirety of one's external environment. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Personal bias suppression
Personal bias suppression is a decrease in the cultural biases that a person filters their perception through. It is most commonly induced under the influence of hallucinogenic substances.
Open full explainer on EffectIndex↗Personal meaning enhancement
Personal meaning enhancement (also known as aberrant salience) is the experience of a considerably increased sense of personal significance becoming attributed to innocuous situations, and coincidences. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, cannabinoids, and deliriants.
Open full explainer on EffectIndex↗Spirituality enhancement
Spirituality enhancement can be described as the experience of a shift in a person’s personal beliefs regarding their existence and place within the universe, their relationship to others, and what they value as meaningful in life. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Thought acceleration
Thought acceleration (also known as racing thoughts) is the experience of thought processes being sped up significantly in comparison to that of everyday sobriety. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, modafinil, and MDMA.
Open full explainer on EffectIndex↗Thought connectivity
Thought connectivity is an alteration of a person's thought stream which is characterized by a distinct increase in wandering thoughts which connect into each other through a fluid association of ideas. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Thought loops
A thought loop is the experience of becoming trapped within a chain of thoughts, actions and emotions which repeats itself over and over again in a cyclic loop. Thought loops are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics and dissociatives. However, they can also occur to a lesser extent under the influence of extremely heavy dosages of stimulants and benzodiazepines.
Open full explainer on EffectIndex↗Time distortion
Time distortion is an effect that makes the passage of time feel wildly altered and difficult to keep track of. is most commonly induced under the influence of strong dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Unity and interconnectedness
Unity and interconnectedness refers to a feeling in which one's sense of self becomes temporarily expanded to include one or more concepts or systems that would not typically be included within one’s sense of individual identity. It most commonly occurs under the influence of psychedelic and dissociative compounds, such as LSD, DMT, ayahuasca, mescaline, and ketamine.
Open full explainer on EffectIndex↗Wakefulness
Wakefulness is an increased ability to stay conscious without feeling sleepy combined with a decreased need to sleep. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as stimulants, nootropics, and psychedelics.
Open full explainer on EffectIndex↗No effects match that search.
Timing
Only onset and total duration are available for this route, so an intensity curve would be misleading.
After effects6-36 hours
Testing
Reagent test reference
The available reference includes test-kit notes. Reagents cannot establish identity, purity, or potency.
Marquis: Strong orange
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