Drifting is the experience of the texture, shape, and general structure of objects and scenery appearing progressively warped, melted, and morphed across themselves. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Pupil dilation can be described as the enlargement of the size of a person's pupils under normal lighting conditions. This is most commonly induced under the influence of moderate dosages of a wide variety of serotonergic compounds, such as psychedelics, dissociatives, deliriants, entactogens, various stimulants, and some antidepressants.

Tracers are the experience of visual trails of varying lengths and opacity being left behind moving objects. They are most commonly induced under the influence of mild dosages of psychedelic compounds.

An abnormal heartbeat is any of a group of conditions in which the electrical activity of the heart is irregular. During this state, the heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. An abnormal heartbeat is most commonly induced under the influence of moderate dosages of stimulant and depressant compounds, such as cocaine, methamphetamine, and GABAergics.

Appetite suppression can be described as the experience of a distinct decrease in a person's sense of hunger and appetite in a manner which can result in both a lesser desire to eat food and a decreased enjoyment of its taste. It is most commonly induced under the influence of moderate dosages of stimulant compounds, such as amphetamine, methylphenidate, nicotine, MDMA, and cocaine.

Decreased libido can be described as a distinct decrease in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as, opioids, antipsychotics and SSRI's, and dissociatives.

Dehydration can be described as an uncomfortably dry mouth and feelings of general thirstiness that results due to a lack of water intake. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as, stimulants, psychedelics, opioids, dissociatives, deliriants, cannabinoids, alcohol, and antipsychotics.

Difficulty urinating (also known as urinary retention) can be described as the experience of a decreased ability to pass urine. It is most commonly induced under the influence of heavy dosages of stimulant and opioid compounds, such as heroin, fentanyl, kratom, amphetamine, MDMA, and 4-FA.

A headache can be described as a pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions. They are most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.

Increased bodily temperature or pyrexia can be described as having a body temperature which is above normal baseline. It is most commonly induced under the influence of heavy dosages of stimulant compounds which affect serotonin and 5-HT receptors, dopamine and D receptors and norepinephrine.

Nausea can be described as a sensation of unease and discomfort in the upper stomach combined with an involuntary urge to vomit. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, deliriants, dissociatives, and stimulants.

Perception of bodily heaviness can be described as feeling as if one's body has significantly increased in its weight. This can result in feelings of slowness and sluggishness due to the body seeming difficult, uncomfortable, or impossible to move. It is most commonly induced under the influence of heavy dosages of depressant compounds, such as GABAergics, opioids, and antipsychotics.

Stimulation can be described as an increase in a person's physical energy levels. It is most commonly induced under the influence of stimulant compounds, such as amphetamine, MDMA, and cocaine.

Teeth grinding (also known as bruxism, jaw clenching, and gurning) can be described as a compulsive and often uncontrollable urge to grind one's teeth. It is most commonly induced under the influence of common dosages of stimulant compounds, such as methamphetamine, MDMA, methylphenidate, and cocaine. However, it can also occur under the influence of certain stimulating psychedelics such as 2C-E, DOC, and AMT.

Temporary erectile dysfunction can be described as a difficulty in achieving and maintaining an adequately erect penis for the purpose of sexual intercourse. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants and certain psychedelics. However, it can also occur under the influence of opioids, dissociatives, GABAergics, and deliriants.

Vasoconstriction can be described as a narrowing of the veins and blood vessels which results from a contraction of their muscular wall. It is most commonly induced under the influence of moderate dosages of stimulating psychedelic compounds, such as LSD, 2C-E, and DOC.

Anxiety is medically recognized as the experience of negative feelings of apprehension, worry, and general unease. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as cannabinoids, psychedelics, dissociatives, and deliriants

Cognitive dysphoria (semantically the opposite of euphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of dissatisfaction, and in some cases indifference to the world around them. It is most commonly induced under the influence of moderate dosages of deliriant compounds, such as DPH and datura. However, it can also occur during a stimulant's offset and during the withdrawal symptoms of almost any substance.

Depression medically encompasses a large variety of different mood disorders whose common features are a sad, empty, or irritable mood co-occurring with bodily and cognitive changes that significantly disrupt an individual's ability to function. Within the context of psychoactive substance usage, depressivity is often accompanied by other coinciding effects such as anxiety, irritability and dysphoria.

Feelings of impending doom can be described as sudden sensations of overwhelming fear and urgency based upon the unfounded belief that a negative event is about to occur in the immediate future. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.