PsychonautWiki marks this substance entry as unapproved. Its information may be incomplete or awaiting review.
Dextromethorphan
Also known as dxm, dmo, dm, dex, robitussin, delsym, dexalone, duract
Dextromethorphan
DXM · DMO · DM · Dex
Overview
Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. It is recommended to dose DXM through direct ingestion of the drug, without other active ingrediants such as guaifenesin or doxylamine.
Sources & licencesPsychonautWiki·TripSit·PubChem chemical identifiers
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The SMILES and basic chemical identifiers are resolved from the linked PubChem record. Fracton renders the molecule locally as inline SVG.
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CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OCTags3 tags
Dose
?
See http://dxm.tripsit.me for mg/weight doses, among other things. Deaths have been reported at 25mg/kg
Safety
- Addiction potential
- produces dependence with chronic use and has moderate abuse potential
- Full tolerance
- develops with prolonged and repeated use
- Half tolerance
- 3 - 7 days
- Zero tolerance
- 1 - 2 weeks
- Cross-tolerance with
- dissociatives
EffectsPsychonautWikiEffectIndex
Visual
24After images
After images (also known as palinopsia) are visual perceptions that continue to appear in one's vision after exposure to the original image has ceased. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Autonomous entity
An autonomous entity is the experience of perceived contact with beings that appear to be sentient in their behaviour. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds.
Open full explainer on EffectIndex↗Colour enhancement
Colour enhancement is a perceived intensification of the brightness and vividness of colours in the external environment. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Depth perception distortions
Depth perception distortions are alterations in how a person perceives the distance of various objects within their visual field. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Double vision
Double vision is the experience of seeing duplicated vision, similar to when one crosses their eyes. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as alcohol, quetiapine, ketamine, and DXM.
Open full explainer on EffectIndex↗Drifting
Drifting is the experience of the texture, shape, and general structure of objects and scenery appearing progressively warped, melted, and morphed across themselves. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Environmental cubism
Environmental cubism is a visual segmentation of the external environment into squares and cubes of varying amounts and sizes. It is most commonly induced under the influence of heavy dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Environmental orbism
PsychonautWiki lists Environmental orbism as a reported subjective effect for Dextromethorphan. A concise EffectIndex summary is not available for this entry.
View on PsychonautWiki↗External hallucination
An external hallucination is the perception of a visual hallucination that displays itself seamlessly into the external environment as if it were physically present. They are most commonly induced under the influence of heavy dosages of deliriant compounds.
Open full explainer on EffectIndex↗Frame rate suppression
Frame rate suppression is the perceived reduction in speed at which visual information is processed. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, MXE, PCP, and DXM.
Open full explainer on EffectIndex↗Geometry
Geometry is the experience of a person's field of vision becoming partially or completely encompassed by fast-moving, colourful, and extremely complex geometric patterns, form constants, shapes, fractals, and colours.
Open full explainer on EffectIndex↗Internal hallucination
An internal hallucination is the perception of a visual hallucination that exclusively occurs within an imagined environment that can typically only be viewed with closed eyes, similar to those found within dreams. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Magnification
Magnification is the experience of distant details within one's visual field appearing magnified and closer than they actually are due to both visual enhancements and hallucinatory effects. It is a rare effect that is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Perspective hallucination
A perspective hallucination is an alteration of the perspective through which a given internal or external hallucination is seen through. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Pupil dilation
Pupil dilation can be described as the enlargement of the size of a person's pupils under normal lighting conditions. This is most commonly induced under the influence of moderate dosages of a wide variety of serotonergic compounds, such as psychedelics, dissociatives, deliriants, entactogens, various stimulants, and some antidepressants.
Open full explainer on EffectIndex↗Scenery slicing
Scenery slicing is the experience of a person's visual field appearing to split into separate, cleanly cut sections. These individual slices then proceed to drift slowly away from their original position before disappearing and resetting to normal. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Settings, sceneries, and landscapes
Settings, sceneries, and landscapes are the perceived environments in which the plot of an internal or external hallucination occurs. This effect is capable of manifesting in a seemingly infinite variety of potential places and settings. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Tracers
Tracers are the experience of visual trails of varying lengths and opacity being left behind moving objects. They are most commonly induced under the influence of mild dosages of psychedelic compounds.
Open full explainer on EffectIndex↗Visual acuity suppression
Acuity suppression is the degradation of the sharpness and clarity of one's vision, resulting in vision becoming partially to completely blurred and indistinct. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as alcohol, quetiapine, ketamine, and DXM.
Open full explainer on EffectIndex↗Visual agnosia
Visual agnosia is a partial to complete inability to mentally process visual information, regardless of its clarity. It is most commonly induced under the influence of heavy dosages of dissociative or antipsychotic compounds, such as ketamine, quetiapine, PCP, and DXM.
Open full explainer on EffectIndex↗Visual disconnection
Visual disconnection is the experience of becoming distanced and/or detached from one's sense of vision. It is a near-universal effect under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Visual haze
Visual haze distorts the surrounding environment to make it appear as if the air is shrouded in an imaginary cloud of smoke, fog, or haze. It is most commonly induced under the influence of mild dosages of hallucinogenic compounds, such as psychedelics, deliriants, and cannabinoids.
Open full explainer on EffectIndex↗Visual processing acceleration
Visual processing acceleration increases the speed at which a person can perceive and interpret rapidly occurring events. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Visual stretching
Visual stretching distorts a person's field of view to make it appear as if it is horizontally or vertically stretching in its size. It is most commonly induced under the influence of heavy dosages of sudden onset hallucinogenic compounds, such as nitrous oxide, DMT, and salvia divinorum. This holds particularly true in the moments immediately preceding ego death.
Open full explainer on EffectIndex↗Emotional & social
1Physical euphoria
Physical euphoria can be described as feelings of pleasure and comfort within and across one's body. This euphoria typically feels somewhat comparable to the endorphin rushes felt during states of excitement or love, the coziness of a comfortable bed, and the rush of an orgasm. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as opioids, stimulants, psychedelics, and GABAergics.
Open full explainer on EffectIndex↗Physical & bodily
27Appetite suppression
Appetite suppression can be described as the experience of a distinct decrease in a person's sense of hunger and appetite in a manner which can result in both a lesser desire to eat food and a decreased enjoyment of its taste. It is most commonly induced under the influence of moderate dosages of stimulant compounds, such as amphetamine, methylphenidate, nicotine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Bodily control enhancement
Bodily control enhancement can be described as feeling as if there has been a distinct increase in a person's ability to control their physical body with precision, balance, coordination, and dexterity. It is most commonly induced under the influence of moderate dosages of stimulating psychedelics, such as LSD, 2C-B, and DOC.
Open full explainer on EffectIndex↗Changes in felt bodily form
Changes in felt bodily form can be described as feelings of the body shifting in its perceived physical shape, organization and form in a manner which is typically devoid of accompanying visual alterations. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and Salvinorin A.
Open full explainer on EffectIndex↗Cough suppression
Cough suppression can be described as a decreased desire and need to cough. It is most commonly induced under the influence of moderate dosages of antitussive compounds such as, codeine, pholcodine, dextromethorphan, noscapine, and butamirate.
Open full explainer on EffectIndex↗Decreased libido
Decreased libido can be described as a distinct decrease in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as, opioids, antipsychotics and SSRI's, and dissociatives.
Open full explainer on EffectIndex↗Difficulty urinating
Difficulty urinating (also known as urinary retention) can be described as the experience of a decreased ability to pass urine. It is most commonly induced under the influence of heavy dosages of stimulant and opioid compounds, such as heroin, fentanyl, kratom, amphetamine, MDMA, and 4-FA.
Open full explainer on EffectIndex↗Dizziness
Dizziness can be described as the perception of a spinning or swaying motion which typically causes a difficulty in standing or walking. It is most commonly induced under the influence of heavy dosages of GABAergic depressant compounds, such as benzodiazepines, alcohol, and GHB.
Open full explainer on EffectIndex↗Gait alteration
Gait alteration is a change in the manner that a person walks and generally moves about throughout their environment. It is most commonly induced under the influence of moderate dosages of dissociatives such as ketamine, and especially DXM.
Open full explainer on EffectIndex↗Increased blood pressure
Increased blood pressure can be described as a condition in which the pressure in the systemic arteries is elevated to abnormal levels. It is most commonly induced under the influence of heavy dosages of deliriants and vasoconstricting compounds, such as traditional stimulants and stimulating psychedelics.
Open full explainer on EffectIndex↗Increased bodily temperature
Increased bodily temperature or pyrexia can be described as having a body temperature which is above normal baseline. It is most commonly induced under the influence of heavy dosages of stimulant compounds which affect serotonin and 5-HT receptors, dopamine and D receptors and norepinephrine.
Open full explainer on EffectIndex↗Increased heart rate
Increased heart rate or tachycardia is described as a heart rate that is faster than the normal heart rate at rest. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.
Open full explainer on EffectIndex↗Increased libido
Increased libido can be described as a distinct increase in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of stimulant compounds, particularly dopaminergic stimulants such as methamphetamine and cocaine.
Open full explainer on EffectIndex↗Increased perspiration
Increased perspiration, or hyperhidrosis, can be described as a condition characterized by increased sweat which is in excess of that required for the regulation of body temperature. It is most commonly induced under the influence of stimulants, psychedelics, and benzodiapine or alcohol withdrawals.
Open full explainer on EffectIndex↗Motor control loss
Motor control loss can be described as feeling as if there has been a distinct decrease in a person's ability to control their physical body with precision, balance, coordination, and dexterity. Motor control loss is often accompanied by other coinciding effects such as sedation and disinhibition. It is most commonly induced under the influence of moderate dosages of GABAergic depressant compounds, such as, alcohol, benzodiazepines, GHB, and phenibut.
Open full explainer on EffectIndex↗Muscle relaxation
Muscle relaxation can be described as the experience of muscles losing their rigidity or tenseness while becoming relaxed and comfortable. It is most commonly induced under the influence of moderate dosages of depressant compounds, such as various benzodiazepines, GABAergics, and opioids.
Open full explainer on EffectIndex↗Nausea
Nausea can be described as a sensation of unease and discomfort in the upper stomach combined with an involuntary urge to vomit. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, deliriants, dissociatives, and stimulants.
Open full explainer on EffectIndex↗Optical sliding
Optical sliding can be described as a physical effect which inhibits the coordination and control of a person's eyes by suppressing their ability to keep them still. It is most commonly induced under the influence of heavy dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Orgasm suppression
Orgasm suppression (formally known as anorgasmia) can be described as a difficulty or complete inability to achieve orgasm despite adequate sexual stimulation. This effect commonly occurs on opioids and dissociatives which have been reported to decrease one's ability to feel sexual pleasure, which may be attributed to their tactile suppressing effects or through some other biological mechanism. It is also a well-known side effect of selective serotonin reuptake inhibitors (SSRIs).
Open full explainer on EffectIndex↗Pain relief
Pain relief can be described as an effect which suppresses negative sensations such as aches and pains. It is most commonly induced under the influence of moderate dosages of a very wide variety of compounds, such as opioids, GABAergics, GABApentinoids, cannabinoids, dissociatives, muscle relaxants, and NSAID's.
Open full explainer on EffectIndex↗Perception of bodily lightness
Perception of bodily lightness can be described as feeling as if one's body has significantly decreased in its weight. This can result in feelings of increased energy and a general sense of bounciness due to the body seeming weightless and therefore effortless to move. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Physical autonomy
Physical autonomy can be described as the experience of a person's own body performing simple or complex actions entirely of its own accord. It is most commonly induced under the influence of heavy dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Physical disconnection
Physical disconnection is the experience of feeling distant and detached from one's sense of touch and their feelings of ownership and control over their own physical body. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as, ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Sedation
Sedation can be described as a decrease in a person's physical energy levels which are interpreted as discouraging when it comes to wakefulness, movement, performing tasks, talkativeness, and general exercise. It is most commonly induced under the influence of moderate dosages of depressant compounds, such as opioids, GABAergics, and antipsychotics.
Open full explainer on EffectIndex↗Spatial disorientation
Spatial disorientation is the failure to perceive or perceiving incorrectly the position, motion, or altitude of oneself within the fixed coordinate system provided by the surface of the Earth and the gravitational vertical. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as diphenidine, ketamine, and DXM.
Open full explainer on EffectIndex↗Stimulation
Stimulation can be described as an increase in a person's physical energy levels. It is most commonly induced under the influence of stimulant compounds, such as amphetamine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Temperature regulation suppression
Temperature regulation suppression can be defined as an inability to maintain a normal temperature. It is most commonly induced under the influence of heavy dosages of stimulating psychedelic compounds, such as LSD, 2C-B, and AMT.
Open full explainer on EffectIndex↗Vibrating vision
Vibrating vision, also known as nystagmus, is the experience of constant, rapid involuntary eye movements in which the eyes shift from left to right in such quick succession that the person's vision begins to vibrate and blur. It is most commonly induced under the influence of heavy dosages of stimulant compounds, such as MDMA, amphetamine, and 4-FA.
Open full explainer on EffectIndex↗Auditory
4Auditory distortion
An auditory distortion is the experience of perceived alterations in how audible noises present and structure themselves. They are most commonly induced under the influence of hallucinogenic compounds.
Open full explainer on EffectIndex↗Auditory enhancement
An auditory enhancement is the experience of an increase or improvement of the acuteness and clarity of sound. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Auditory hallucination
An auditory hallucination is the experience of hearing spontaneous and imaginary noises. They are most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.
Open full explainer on EffectIndex↗Auditory suppression
Auditory suppression is the experience of sound becoming perceived as more distant, quiet, and muffled than they actually are. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Tactile
4Itchiness
Itchiness is the sensation that causes a person the desire or reflex to scratch at their skin. It is most commonly induced under the influence of heavy dosages of opioid compounds, such as heroin, fentanyl, tramadol, and kratom.
Open full explainer on EffectIndex↗Muscle twitching
Muscle twitching can be described as the sensation of small and localised tremblings of muscle groups. These vibrations are often powerful enough to be visibly seen through the skin. It is most commonly induced under the influence of moderate dosages of stimulating psychedelic compounds such as LSD, 2C-E, DOC, and AMT.
Open full explainer on EffectIndex↗Spontaneous tactile sensations
Spontaneous tactile sensations are the experience of sensations across the body occurring without any obvious or immediate physical trigger. This results in feelings of seemingly random yet distinct tingling sensations that occur across the skin and within the body. Depending on the psychoactive substance consumed, these vary greatly in their styles of sensation.
Open full explainer on EffectIndex↗Tactile suppression
Tactile suppression is a decrease in one's ability to feel their sense of touch, which may result in a general numbness across the body. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Smell & taste
1Gustatory hallucination
A gustatory hallucination is any hallucination that involves one's sense of taste. A common example of this is a strong, unpleasant metallic taste in one's mouth. They are most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Cognitive
35Amnesia
Amnesia is a global impairment in the ability to acquire new memories regardless of sensory modality, and a loss of some memories, especially recent ones, from the period before amnesia began. It is most commonly induced under the influence of heavy dosages of GABAergic depressants, such as alcohol, benzodiazepines, GHB, and zolpidem.
Open full explainer on EffectIndex↗Analysis suppression
Analysis suppression is a distinct decrease in a person's overall ability to process information and logically or creatively analyze concepts, ideas, and scenarios. It is most commonly induced under the influence of heavy dosages of antipsychotic compounds, and is associated with long term use of such drugs like quetiapine, haloperidol, and risperidone.
Open full explainer on EffectIndex↗Anxiety
Anxiety is medically recognized as the experience of negative feelings of apprehension, worry, and general unease. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as cannabinoids, psychedelics, dissociatives, and deliriants
Open full explainer on EffectIndex↗Anxiety suppression
Anxiety suppression (also known as anxiolysis or minimal sedation) is medically recognized as a partial to complete suppression of a person’s ability to feel anxiety, general unease, and negative feelings of both psychological and physiological tension. It is most commonly induced under the influence of moderate dosages of anxiolytic compounds which primarily include GABAergic depressants, such as benzodiazepines, alcohol, GHB, and gabapentinoids.
Open full explainer on EffectIndex↗Cognitive disconnection
Cognitive disconnection is the experience of feeling distant and detached from one's sense of identity, thought stream, and general cognitive processes. It is a near-universal effect under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Cognitive euphoria
Cognitive euphoria (semantically the opposite of cognitive dysphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of well-being, elation, happiness, excitement, and joy. It is most commonly induced under the influence of moderate dosages of opioids, entactogens, stimulants, and GABAergic depressants. However, it can also occur to a lesser extent under the influence of hallucinogenic compounds such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Cognitive fatigue
Cognitive fatigue (also called exhaustion, tiredness, lethargy, languidness, languor, lassitude, and listlessness) is medically recognized as a state usually associated with a weakening or depletion of one's mental resources. It is most commonly induced under the influence of moderate dosages of antipsychotic compounds, such as quetiapine, haloperidol, and risperidone.
Open full explainer on EffectIndex↗Conceptual thinking
Conceptual thinking is an alteration to the nature and content of one's internal thought stream. This alteration predisposes a user to think thoughts that are no longer primarily comprised of words and linear sentence structures. Instead, thoughts become equally comprised of what is perceived to be extremely detailed renditions of the innately understandable and internally stored concepts that words exist to label. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics and dissociatives.
Open full explainer on EffectIndex↗Confusion
Confusion is an impairment of abstract thinking demonstrated by an inability to think with one’s customary clarity and coherence. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, synthetic cannabinoids, and deliriants.
Open full explainer on EffectIndex↗Creativity enhancement
Creativity enhancement is a perceived increase in one's capability to imagine new ideas, create art, or think about existing concepts in a novel manner. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Deja vu
Déjà Vu or Deja Vu can be described as the sudden sensation that a current event or situation has already been experienced at some point in the past when, in actuality, it hasn't. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Delusion
A delusion is a false idea or belief that is held with strong conviction and subjective certainty and is inconsistent with an individual’s educational, cultural and social background. Delusions are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.
Open full explainer on EffectIndex↗Depersonalization
Depersonalization is medically recognized as the experience of feeling detached from one's mental processes, body, or actions as if they are an outside observer. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Derealization
Derealization or derealisation (sometimes abbreviated as DR) is the experience of feeling detached from, and as if one is an outside observer of, one's surroundings (e.g., individuals or objects are experienced as unreal, dreamlike, foggy, lifeless, or visually distorted). It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Disinhibition
Disinhibition is medically recognized as an orientation towards immediate gratification, leading to impulsive behavior driven by current thoughts, feelings, and external stimuli, without regard for past learning or consideration of future consequences. It is most commonly induced under the influence of moderate dosages of GABAergic depressants, such as alcohol, benzodiazepines, phenibut, and GHB.
Open full explainer on EffectIndex↗Dream potentiation
Dream potentiation is an effect that increases the subjective intensity, vividness, and frequency of sleeping dream states. It is most commonly induced under the influence of moderate dosages of oneirogenic compounds, a class of hallucinogen that is used to specifically potentiate dreams when taken before sleep.
Open full explainer on EffectIndex↗Ego inflation
Ego inflation is an effect that magnifies and enhances one's own ego and self-regard, resulting in the person feeling an increased sense of confidence, superiority, and general arrogance. It is most commonly induced under the influence of moderate dosages of stimulant compounds, particularly dopaminergic stimulants, such as methamphetamine and cocaine.
Open full explainer on EffectIndex↗Emotion intensification
Emotion intensification is an increase in a person's current emotional state beyond normal levels of intensity. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Empathy, affection, and sociability enhancement
Empathy, affection, and sociability enhancement is the experience of a mind state that is dominated by intense feelings of compassion, talkativeness, and happiness. It is most commonly induced under the influence of moderate dosages of entactogenic compounds, such as MDMA, 4-FA, and 2C-B.
Open full explainer on EffectIndex↗Existential self-realization
Existential self-realization can be described as a sudden realization, revelation, or reaffirmation of a person's existence within this universe. Existential self-realization is most commonly induced under the influence of moderate dosages of psychedelic and dissociative compounds such as ketamine, LSD, 4-AcO-DMT, and DCK.
Open full explainer on EffectIndex↗Focus suppression
Focus suppression is medically recognized as a decreased ability to selectively concentrate on an aspect of the environment while ignoring other things. It is most commonly induced under the influence of moderate or heavy dosages of antipsychotics, benzodiazepines, cannabinoids, and hallucinogens.
Open full explainer on EffectIndex↗Immersion enhancement
Immersion enhancement is an effect that results in a pronounced increase in one's tendency to become fully captivated and engrossed by external stimuli, such as film, TV shows, video games, and various other forms of media. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.
Open full explainer on EffectIndex↗Increased music appreciation
Increased music appreciation is a general sense of an increased enjoyment of music. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids
Open full explainer on EffectIndex↗Increased sense of humor
Increased sense of humor is as a general enhancement of the likelihood and degree to which a person finds stimuli to be humorous and amusing. It is most commonly induced under the influence of moderate dosages of certain hallucinogenic compounds, such as psychedelics, mescaline, and cannabinoids.
Open full explainer on EffectIndex↗Memory suppression
Memory suppression is an inhibition of a person's ability to maintain a functional short and long-term memory. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Motivation suppression
Motivation suppression (also known as avolition or amotivation) is a decreased desire to initiate or persist in goal-directed behavior. It is most commonly induced under the influence of an acute dosage of an antipsychotic compound, such as quetiapine, haloperidol, and risperidone. However, it is worth noting that chronic treatment with any dose of antipsychotic medication does not cause this effect.
Open full explainer on EffectIndex↗Novelty enhancement
Novelty enhancement is a feeling of increased fascination, awe, and appreciation attributed to specific parts or the entirety of one's external environment. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Personal bias suppression
Personal bias suppression is a decrease in the cultural biases that a person filters their perception through. It is most commonly induced under the influence of hallucinogenic substances.
Open full explainer on EffectIndex↗Personal meaning enhancement
Personal meaning enhancement (also known as aberrant salience) is the experience of a considerably increased sense of personal significance becoming attributed to innocuous situations, and coincidences. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, cannabinoids, and deliriants.
Open full explainer on EffectIndex↗Sleepiness
Sleepiness (also known as drowsiness) is medically recognized as a state of near-sleep, or a strong desire for sleep without feeling a decrease in one's physical energy levels. This state is independent of a circadian rhythm; so, unlike sedation, this effect does not necessarily decrease physical energy levels but instead decreases wakefulness. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as cannabinoids, GABAergic depressants, opioids, antipsychotics, some antihistamines, and certain psychedelics.
Open full explainer on EffectIndex↗Spirituality enhancement
Spirituality enhancement can be described as the experience of a shift in a person’s personal beliefs regarding their existence and place within the universe, their relationship to others, and what they value as meaningful in life. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Thought deceleration
Thought deceleration is the process of thought being slowed down significantly in comparison to that of normal sobriety. It is most commonly induced under the influence of heavy dosages of depressant compounds, such as GABAergics, antipsychotics, and opioids.
Open full explainer on EffectIndex↗Time distortion
Time distortion is an effect that makes the passage of time feel wildly altered and difficult to keep track of. is most commonly induced under the influence of strong dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Unity and interconnectedness
Unity and interconnectedness refers to a feeling in which one's sense of self becomes temporarily expanded to include one or more concepts or systems that would not typically be included within one’s sense of individual identity. It most commonly occurs under the influence of psychedelic and dissociative compounds, such as LSD, DMT, ayahuasca, mescaline, and ketamine.
Open full explainer on EffectIndex↗Wakefulness
Wakefulness is an increased ability to stay conscious without feeling sleepy combined with a decreased need to sleep. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as stimulants, nootropics, and psychedelics.
Open full explainer on EffectIndex↗Transpersonal & hallucinatory
1Scenarios and plots
Scenarios and plots are the situations, stories, and events that occur within both external and internal hallucinations. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.
Open full explainer on EffectIndex↗Other
3Peripheral vision enhancement
PsychonautWiki lists Peripheral vision enhancement as a reported subjective effect for Dextromethorphan. A concise EffectIndex summary is not available for this entry.
View on PsychonautWiki↗Perspective distortion
PsychonautWiki lists Perspective distortion as a reported subjective effect for Dextromethorphan. A concise EffectIndex summary is not available for this entry.
View on PsychonautWiki↗Synaesthesia
Synaesthesia (also spelt synesthesia or synæsthesia) is the experience of a blending, merging, or mixing of the senses. Synaesthesia is commonly induced under the influence of heavy dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗No effects match that search.
Timing
Only onset and total duration are available for this route, so an intensity curve would be misleading.
After effects4-24 hours
Testing
No testing reference is available for this substance.
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